An Empirical Bayesian Method for Detecting Differentially Expressed Genes Using EST Data

Detection of differentially expressed genes from expressed sequence tags (ESTs) data has received much attention. An empirical Bayesian method is introduced in which gene expression patterns are estimated and used to define detection statistics. Significantly differentially expressed genes can be de...

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Detalles Bibliográficos
Autores principales: You, Na, Liu, Junmei, Mao, Chang Xuan
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2277491/
https://www.ncbi.nlm.nih.gov/pubmed/18389067
http://dx.doi.org/10.1155/2008/817210
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author You, Na
Liu, Junmei
Mao, Chang Xuan
author_facet You, Na
Liu, Junmei
Mao, Chang Xuan
author_sort You, Na
collection PubMed
description Detection of differentially expressed genes from expressed sequence tags (ESTs) data has received much attention. An empirical Bayesian method is introduced in which gene expression patterns are estimated and used to define detection statistics. Significantly differentially expressed genes can be declared given detection statistics. Simulation is done to evaluate the performance of proposed method. Two real applications are studied.
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spelling pubmed-22774912008-11-06 An Empirical Bayesian Method for Detecting Differentially Expressed Genes Using EST Data You, Na Liu, Junmei Mao, Chang Xuan Int J Plant Genomics Research Article Detection of differentially expressed genes from expressed sequence tags (ESTs) data has received much attention. An empirical Bayesian method is introduced in which gene expression patterns are estimated and used to define detection statistics. Significantly differentially expressed genes can be declared given detection statistics. Simulation is done to evaluate the performance of proposed method. Two real applications are studied. Hindawi Publishing Corporation 2008 2008-03-13 /pmc/articles/PMC2277491/ /pubmed/18389067 http://dx.doi.org/10.1155/2008/817210 Text en Copyright © 2008 Na You et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
You, Na
Liu, Junmei
Mao, Chang Xuan
An Empirical Bayesian Method for Detecting Differentially Expressed Genes Using EST Data
title An Empirical Bayesian Method for Detecting Differentially Expressed Genes Using EST Data
title_full An Empirical Bayesian Method for Detecting Differentially Expressed Genes Using EST Data
title_fullStr An Empirical Bayesian Method for Detecting Differentially Expressed Genes Using EST Data
title_full_unstemmed An Empirical Bayesian Method for Detecting Differentially Expressed Genes Using EST Data
title_short An Empirical Bayesian Method for Detecting Differentially Expressed Genes Using EST Data
title_sort empirical bayesian method for detecting differentially expressed genes using est data
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2277491/
https://www.ncbi.nlm.nih.gov/pubmed/18389067
http://dx.doi.org/10.1155/2008/817210
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