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Phosphorylation at serines 104 and 106 by Erk1/2 MAPK is important for estrogen receptor-α activity

Phosphorylation of estrogen receptor-α (ERα) at specific residues in transcription activation function 1 (AF-1) can stimulate ERα activity in a ligand-independent manner. This has led to the proposal that AF-1 phosphorylation and the consequent increase in ERα activity could contribute to resistance...

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Detalles Bibliográficos
Autores principales:	Thomas, Ross S, Sarwar, Naveed, Phoenix, Fladia, Coombes, R Charles, Ali, Simak
Formato:	Texto
Lenguaje:	English
Publicado:	Society for Endocrinology 2008
Materias:	Regular papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2277492/ https://www.ncbi.nlm.nih.gov/pubmed/18372406 http://dx.doi.org/10.1677/JME-07-0165

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