Evaluation of Paired-End Sequencing Strategies for Detection of Genome Rearrangements in Cancer

Paired-end sequencing is emerging as a key technique for assessing genome rearrangements and structural variation on a genome-wide scale. This technique is particularly useful for detecting copy-neutral rearrangements, such as inversions and translocations, which are common in cancer and can produce...

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Detalles Bibliográficos
Autores principales: Bashir, Ali, Volik, Stanislav, Collins, Colin, Bafna, Vineet, Raphael, Benjamin J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2278375/
https://www.ncbi.nlm.nih.gov/pubmed/18404202
http://dx.doi.org/10.1371/journal.pcbi.1000051

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