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Identification of CIITA Regulated Genetic Module Dedicated for Antigen Presentation

The class II trans-activator CIITA is a transcriptional co-activator required for the expression of Major Histocompatibility Complex (MHC) genes. Although the latter function is well established, the global target-gene specificity of CIITA had not been defined. We therefore generated a comprehensive...

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Detalles Bibliográficos
Autores principales: Krawczyk, Michal, Seguín-Estévez, Queralt, Leimgruber, Elisa, Sperisen, Peter, Schmid, Christoph, Bucher, Philipp, Reith, Walter
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2278383/
https://www.ncbi.nlm.nih.gov/pubmed/18437201
http://dx.doi.org/10.1371/journal.pgen.1000058