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Selection against tandem splice sites affecting structured protein regions

BACKGROUND: Alternative selection of splice sites in tandem donors and acceptors is a major mode of alternative splicing. Here, we analyzed whether in-frame tandem sites leading to subtle mRNA insertions/deletions of 3, 6, or 9 nucleotides are under natural selection. RESULTS: We found multiple line...

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Detalles Bibliográficos
Autores principales: Hiller, Michael, Szafranski, Karol, Huse, Klaus, Backofen, Rolf, Platzer, Matthias
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279118/
https://www.ncbi.nlm.nih.gov/pubmed/18366714
http://dx.doi.org/10.1186/1471-2148-8-89

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