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FOXP3(+ )T(regs )and B7-H1(+)/PD-1(+ )T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy

BACKGROUND: Recent studies have demonstrated a direct involvement of B7-H1, PD-1 and FOXP3 molecules in the immune escape of cancer. B7-H1 is an inhibitory molecule that binds to PD-1 on T lymphocytes, while FOXP3 is a marker for regulatory T cells (T(regs)). We have previously demonstrated the asso...

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Detalles Bibliográficos
Autores principales:	Ghebeh, Hazem, Barhoush, Eman, Tulbah, Asma, Elkum, Naser, Al-Tweigeri, Taher, Dermime, Said
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279136/ https://www.ncbi.nlm.nih.gov/pubmed/18294387 http://dx.doi.org/10.1186/1471-2407-8-57

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