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Roles of GRK and PDE4 Activities in the Regulation of β(2) Adrenergic Signaling

An important focus in cell biology is understanding how different feedback mechanisms regulate G protein–coupled receptor systems. Toward this end we investigated the regulation of endogenous β(2) adrenergic receptors (β2ARs) and phosphodiesterases (PDEs) by measuring cAMP signals in single HEK-293...

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Detalles Bibliográficos
Autores principales: Xin, Wenkuan, Tran, Tuan M., Richter, Wito, Clark, Richard B., Rich, Thomas C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279169/
https://www.ncbi.nlm.nih.gov/pubmed/18347080
http://dx.doi.org/10.1085/jgp.200709881