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Roles of GRK and PDE4 Activities in the Regulation of β(2) Adrenergic Signaling
An important focus in cell biology is understanding how different feedback mechanisms regulate G protein–coupled receptor systems. Toward this end we investigated the regulation of endogenous β(2) adrenergic receptors (β2ARs) and phosphodiesterases (PDEs) by measuring cAMP signals in single HEK-293...
Autores principales: | Xin, Wenkuan, Tran, Tuan M., Richter, Wito, Clark, Richard B., Rich, Thomas C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279169/ https://www.ncbi.nlm.nih.gov/pubmed/18347080 http://dx.doi.org/10.1085/jgp.200709881 |
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