Cargando…
Chlamydial Entry Involves TARP Binding of Guanine Nucleotide Exchange Factors
Chlamydia trachomatis attachment to cells induces the secretion of the elementary body–associated protein TARP (Translocated Actin Recruiting Protein). TARP crosses the plasma membrane where it is immediately phosphorylated at tyrosine residues by unknown host kinases. The Rac GTPase is also activat...
Autores principales: | Lane, B. Josh, Mutchler, Charla, Al Khodor, Souhaila, Grieshaber, Scott S., Carabeo, Rey A. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2279300/ https://www.ncbi.nlm.nih.gov/pubmed/18383626 http://dx.doi.org/10.1371/journal.ppat.1000014 |
Ejemplares similares
-
Dynamin-dependent entry of Chlamydia trachomatis is sequentially regulated by the effectors TarP and TmeA
por: Romero, Matthew D., et al.
Publicado: (2023) -
The Conserved Tarp Actin Binding Domain Is Important for Chlamydial Invasion
por: Jewett, Travis J., et al.
Publicado: (2010) -
The Chlamydia Effector TarP Mimics the Mammalian Leucine-Aspartic Acid Motif of Paxillin to Subvert the Focal Adhesion Kinase during Invasion
por: Thwaites, Tristan, et al.
Publicado: (2014) -
Chlamydial virulence factor TarP mimics talin to disrupt the talin‐vinculin complex
por: Whitewood, Austin J., et al.
Publicado: (2018) -
Vinculin Interacts with the Chlamydia Effector TarP Via a Tripartite Vinculin Binding Domain to Mediate Actin Recruitment and Assembly at the Plasma Membrane
por: Thwaites, Tristan R., et al.
Publicado: (2015)