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The eIF4E RNA regulon promotes the Akt signaling pathway

Eukaryotic initiation factor 4E (eIF4E) promotes cellular proliferation and can rescue cells from apoptotic stimuli such as serum starvation. However, the mechanisms underlying apoptotic rescue are not well understood. In this study, we demonstrate that eIF4E overexpression leads to enhanced surviva...

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Detalles Bibliográficos
Autores principales: Culjkovic, Biljana, Tan, Keith, Orolicki, Slobodanka, Amri, Abdellatif, Meloche, Sylvain, Borden, Katherine L.B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2287285/
https://www.ncbi.nlm.nih.gov/pubmed/18391071
http://dx.doi.org/10.1083/jcb.200707018

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