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The eIF4E RNA regulon promotes the Akt signaling pathway
Eukaryotic initiation factor 4E (eIF4E) promotes cellular proliferation and can rescue cells from apoptotic stimuli such as serum starvation. However, the mechanisms underlying apoptotic rescue are not well understood. In this study, we demonstrate that eIF4E overexpression leads to enhanced surviva...
Autores principales: | Culjkovic, Biljana, Tan, Keith, Orolicki, Slobodanka, Amri, Abdellatif, Meloche, Sylvain, Borden, Katherine L.B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2287285/ https://www.ncbi.nlm.nih.gov/pubmed/18391071 http://dx.doi.org/10.1083/jcb.200707018 |
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