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Latency Associated Peptide Has In Vitro and In Vivo Immune Effects Independent of TGF-β1

Latency Associated Peptide (LAP) binds TGF-β1, forming a latent complex. Currently, LAP is presumed to function only as a sequestering agent for active TGF-β1. Previous work shows that LAP can induce epithelial cell migration, but effects on leukocytes have not been reported. Because of the multipli...

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Detalles Bibliográficos
Autores principales: Ali, Naeem A., Gaughan, Alice A., Orosz, Charles G., Baran, Chris P., McMaken, Sara, Wang, Yijie, Eubank, Timothy D., Hunter, Melissa, Lichtenberger, Frank J., Flavahan, Nicholas A., Lawler, Jack, Marsh, Clay B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2288562/
https://www.ncbi.nlm.nih.gov/pubmed/18392110
http://dx.doi.org/10.1371/journal.pone.0001914

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