Cargando…

Potential Therapeutic Targets for PPARγ after Spinal Cord Injury

Traumatic injury to the spinal cord results in multiple anatomical, physiological, and functional deficits as a result of local neuronal and glial cell death as well as loss of descending and ascending axons traversing the injury site. The many different mechanisms thought to contribute to protracte...

Descripción completa

Detalles Bibliográficos
Autor principal:	McTigue, Dana M.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2008
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2288640/ https://www.ncbi.nlm.nih.gov/pubmed/18401444 http://dx.doi.org/10.1155/2008/517162

Ejemplares similares

Delayed short-term tamoxifen treatment does not promote remyelination or neuron sparing after spinal cord injury
por: Pukos, Nicole, et al.
Publicado: (2020)

PPAR agonists as therapeutics for CNS trauma and neurological diseases
por: Mandrekar-Colucci, Shweta, et al.
Publicado: (2013)

The fate of proliferating cells in the injured adult spinal cord
por: McTigue, Dana M, et al.
Publicado: (2011)

Alpha-synuclein increases in rodent and human spinal cord injury and promotes inflammation and tissue loss
por: Sauerbeck, Andrew D., et al.
Publicado: (2021)

Inhibition of astroglial NF-kappaB enhances oligodendrogenesis following spinal cord injury
por: Bracchi-Ricard, Valerie, et al.
Publicado: (2013)

PPAR-γ: Therapeutic Potential for Multiple Sclerosis
por: Drew, Paul D., et al.
Publicado: (2008)

Therapeutic Potential of PPARγ Activation in Stroke
por: Vemuganti, Raghu
Publicado: (2008)

Improved Gene Delivery to Adult Mouse Spinal Cord Through the Use of Engineered Hybrid Adeno-Associated Viral serotypes
por: Siu, Jason J., et al.
Publicado: (2017)

PPARγ Agonists: Potential as Therapeutics for Neovascular Retinopathies
por: Pershadsingh, Harrihar A., et al.
Publicado: (2008)

Sub-cellular In-situ Characterization of Ferritin(iron) in a Rodent Model of Spinal Cord Injury
por: Blissett, A. R., et al.
Publicado: (2018)

RAR/RXR and PPAR/RXR Signaling in Spinal Cord Injury
por: van Neerven, Sabien, et al.
Publicado: (2007)

Therapeutic potential of PPARγ natural agonists in liver diseases
por: Wu, Liwei, et al.
Publicado: (2020)

Molecular evidence for the involvement of PPAR-δ and PPAR-γ in anti-inflammatory and neuroprotective activities of palmitoylethanolamide after spinal cord trauma
por: Paterniti, Irene, et al.
Publicado: (2013)

PPARγ as a Novel Therapeutic Target in Lung Cancer
por: Reddy, Aravind T., et al.
Publicado: (2016)

Ferroptosis: a critical player and potential therapeutic target in traumatic brain injury and spinal cord injury
por: Li, Qing-Sheng, et al.
Publicado: (2022)

The Proteostasis Network: A Global Therapeutic Target for Neuroprotection after Spinal Cord Injury
por: Whittemore, Scott R., et al.
Publicado: (2022)

Sirtuins: Potential Therapeutic Targets for Defense against Oxidative Stress in Spinal Cord Injury
por: Lin, Jialiang, et al.
Publicado: (2021)

Therapeutic approaches for spinal cord injury
por: Cristante, Alexandre Fogaça, et al.
Publicado: (2012)

Therapeutic Implications of PPARγ in Human Osteosarcoma
por: Wagner, Eric R., et al.
Publicado: (2010)

Therapeutic Implications of PPARγ in Cardiovascular Diseases
por: Hasegawa, Hiroshi, et al.
Publicado: (2010)

microRNAs in Spinal Cord Injury: Potential Roles and Therapeutic Implications
por: Ning, Bin, et al.
Publicado: (2014)

Inhibiting the kynurenine pathway in spinal cord injury: multiple therapeutic potentials?
por: Jacobs, Kelly R., et al.
Publicado: (2018)

PPARγ as a therapeutic target to rescue mitochondrial function in neurological disease
por: Corona, Juan Carlos, et al.
Publicado: (2016)

The Nuclear Hormone Receptor PPAR(γ) as a Therapeutic Target in Major Diseases
por: Schmidt, Martina Victoria, et al.
Publicado: (2010)

The therapeutic potential of inhibiting PPARγ phosphorylation to treat type 2 diabetes
por: Frkic, Rebecca L., et al.
Publicado: (2021)

Pathophysiology and Therapeutic Approaches for Spinal Cord Injury
por: Lima, Rui, et al.
Publicado: (2022)

Osteoporosis after spinal cord injury: aetiology, effects and therapeutic approaches
por: Abdelrahman, Shima, et al.
Publicado: (2021)

PPARγ and PGC-1α as Therapeutic Targets in Parkinson’s
por: Corona, Juan Carlos, et al.
Publicado: (2014)

Understanding PPARγ and Its Agonists on Trophoblast Differentiation and Invasion: Potential Therapeutic Targets for Gestational Diabetes Mellitus and Preeclampsia
por: Qin, Yushu, et al.
Publicado: (2023)

Lentiviral Vectors Delivered with Biomaterials as Therapeutics for Spinal Cord Injury
por: Shortiss, Ciara, et al.
Publicado: (2021)

Repurposing Small Molecules to Target PPAR-γ as New Therapies for Peripheral Nerve Injuries
por: Rayner, Melissa L. D., et al.
Publicado: (2021)

Therapeutic effect of umbilical cord blood cells on spinal cord injury
por: Zhang, Jun‐Yan, et al.
Publicado: (2023)

PPAR-γ, Microglial Cells, and Ocular Inflammation: New Venues for Potential Therapeutic Approaches
por: Malchiodi-Albedi, Fiorella, et al.
Publicado: (2008)

Targeting mitoNEET with pioglitazone for therapeutic neuroprotection after spinal cord injury
por: Rabchevsky, Alexander G., et al.
Publicado: (2017)

Therapeutic Advantages of Dual Targeting of PPAR-δ and PPAR-γ in an Experimental Model of Sporadic Alzheimer’s Disease
por: Reich, D, et al.
Publicado: (2018)

Examining the properties and therapeutic potential of glial restricted precursors in spinal cord injury
por: Hayakawa, Kazuo, et al.
Publicado: (2016)

Therapeutic Strategies Targeting Respiratory Recovery after Spinal Cord Injury: From Preclinical Development to Clinical Translation
por: Michel-Flutot, Pauline, et al.
Publicado: (2023)

The Ubiquitin-Proteasome System: Potential Therapeutic Targets for Alzheimer’s Disease and Spinal Cord Injury
por: Gong, Bing, et al.
Publicado: (2016)

Elevated intraspinal pressure in traumatic spinal cord injury is a promising therapeutic target
por: Yang, Chao-Hua, et al.
Publicado: (2022)

Therapeutic Potential of Niche-Specific Mesenchymal Stromal Cells for Spinal Cord Injury Repair
por: Lindsay, Susan L., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_8sf92lgjj8tib0og75eact2pkv