Vpr14-88-Apobec3G Fusion Protein Is Efficiently Incorporated into Vif-Positive HIV-1 Particles and Inhibits Viral Infection

BACKGROUND: APOBEC3G (A3G), a deoxycytidine deaminase, is a potent host antiviral factor that can restrict HIV-1 infection. During Vif-negative HIV-1 replication, A3G is incorporated into HIV-1 particles, induces mutations in reverse transcribed viral DNA and inhibits reverse transcription. However,...

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Detalles Bibliográficos
Autores principales: Ao, Zhujun, Yu, Zhe, Wang, Lina, Zheng, Yingfeng, Yao, Xiaojian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2288674/
https://www.ncbi.nlm.nih.gov/pubmed/18414671
http://dx.doi.org/10.1371/journal.pone.0001995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2288674/
https://www.ncbi.nlm.nih.gov/pubmed/18414671
http://dx.doi.org/10.1371/journal.pone.0001995

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