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Mutagenesis of the human transferrin receptor: two cytoplasmic phenylalanines are required for efficient internalization and a second- site mutation is capable of reverting an internalization-defective phenotype
Site-specific mutagenesis has been used to define the sequences required for efficient internalization of the human transferrin receptor. It has previously been shown that the sole cytoplasmic tyrosine, at position 20, is required for efficient internalization. When two other cytoplasmic aromatic re...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1991
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2288869/ https://www.ncbi.nlm.nih.gov/pubmed/1900298 |