Cargando…
Insulin receptors internalize by a rapid, saturable pathway requiring receptor autophosphorylation and an intact juxtamembrane region
The effect of receptor occupancy on insulin receptor endocytosis was examined in CHO cells expressing normal human insulin receptors (CHO/IR), autophosphorylation- and internalization-deficient receptors (CHO/IRA1018), and receptors which undergo autophosphorylation but lack a sequence required for...
Formato: | Texto |
---|---|
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1991
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289201/ https://www.ncbi.nlm.nih.gov/pubmed/1757462 |
Ejemplares similares
-
The insulin receptor juxtamembrane region contains two independent tyrosine/beta-turn internalization signals
Publicado: (1992) -
The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors
por: Kornilov, F. D., et al.
Publicado: (2023) -
Autoinhibition of the Ron receptor tyrosine kinase by the juxtamembrane domain
por: Wang, Xin, et al.
Publicado: (2014) -
Ligand-mediated autophosphorylation activity of the epidermal growth factor receptor during internalization
Publicado: (1989) -
The juxtamembrane regions of human receptor tyrosine kinases exhibit conserved interaction sites with anionic lipids
por: Hedger, George, et al.
Publicado: (2015)