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Dissecting microregulation of a master regulatory network

BACKGROUND: The master regulator p53 tumor-suppressor protein through coordination of several downstream target genes and upstream transcription factors controls many pathways important for tumor suppression. While it has been reported that some of the p53's functions are microRNA-mediated, it...

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Detalles Bibliográficos
Autores principales: Sinha, Amit U, Kaimal, Vivek, Chen, Jing, Jegga, Anil G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289817/
https://www.ncbi.nlm.nih.gov/pubmed/18294391
http://dx.doi.org/10.1186/1471-2164-9-88