Different bacterial gene expression patterns and attenuated host immune responses are associated with the evolution of low-level vancomycin resistance during persistent methicillin-resistant Staphylococcus aureus bacteraemia

BACKGROUND: Low-level vancomycin resistance in Staphylococcus aureus (vancomycin-intermediate S. aureus (VISA) and hetero-VISA [hVISA]) emerges during persistent infection and failed vancomycin therapy. Up-regulation of genes associated with the "cell wall stimulon" and mutations in the vr...

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Detalles Bibliográficos
Autores principales: Howden, Benjamin P, Smith, Danielle J, Mansell, Ashley, Johnson, Paul DR, Ward, Peter B, Stinear, Timothy P, Davies, John K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289824/
https://www.ncbi.nlm.nih.gov/pubmed/18304359
http://dx.doi.org/10.1186/1471-2180-8-39

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