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Binding-Induced Folding of a Natively Unstructured Transcription Factor

Transcription factors are central components of the intracellular regulatory networks that control gene expression. An increasingly recognized phenomenon among human transcription factors is the formation of structure upon target binding. Here, we study the folding and binding of the pKID domain of...

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Detalles Bibliográficos
Autores principales: Turjanski, Adrian Gustavo, Gutkind, J. Silvio, Best, Robert B., Hummer, Gerhard
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289845/
https://www.ncbi.nlm.nih.gov/pubmed/18404207
http://dx.doi.org/10.1371/journal.pcbi.1000060