An AP Endonuclease 1–DNA Polymerase β Complex: Theoretical Prediction of Interacting Surfaces

Abasic (AP) sites in DNA arise through both endogenous and exogenous mechanisms. Since AP sites can prevent replication and transcription, the cell contains systems for their identification and repair. AP endonuclease (APEX1) cleaves the phosphodiester backbone 5′ to the AP site. The cleavage, a key...

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Detalles Bibliográficos
Autores principales: Abyzov, Alexej, Uzun, Alper, Strauss, Phyllis R., Ilyin, Valentin A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289873/
https://www.ncbi.nlm.nih.gov/pubmed/18437203
http://dx.doi.org/10.1371/journal.pcbi.1000066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289873/
https://www.ncbi.nlm.nih.gov/pubmed/18437203
http://dx.doi.org/10.1371/journal.pcbi.1000066

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