Pathways to Injury in Chronic Pancreatitis: Decoding the Role of the High-Risk SPINK1 N34S Haplotype Using Meta-Analysis

BACKGROUND: The complex interactions between recurrent trypsin-mediated pancreatic injury, alcohol-associated pancreatic injury and SPINK1 polymorphisms in chronic pancreatitis (CP) are undefined. We hypothesize that CP occurs as a result of multiple pathological mechanisms (pathways) that are initi...

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Detalles Bibliográficos
Autores principales: Aoun, Elie, Chang, Chung-Chou H., Greer, Julia B., Papachristou, Georgios I., Barmada, M. Michael, Whitcomb, David C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289874/
https://www.ncbi.nlm.nih.gov/pubmed/18414673
http://dx.doi.org/10.1371/journal.pone.0002003

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