The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer Growth

Numerous longevity genes have been discovered in model organisms and altering their function results in prolonged lifespan. In mammals, some have speculated that any health benefits derived from manipulating these same pathways might be offset by increased cancer risk on account of their propensity...

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Detalles Bibliográficos
Autores principales: Firestein, Ron, Blander, Gil, Michan, Shaday, Oberdoerffer, Philipp, Ogino, Shuji, Campbell, Jennifer, Bhimavarapu, Anupama, Luikenhuis, Sandra, de Cabo, Rafael, Fuchs, Charles, Hahn, William C., Guarente, Leonard P., Sinclair, David A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2289879/
https://www.ncbi.nlm.nih.gov/pubmed/18414679
http://dx.doi.org/10.1371/journal.pone.0002020

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