Cargando…

Long term survival after coronary endarterectomy in patients undergoing combined coronary and valvular surgery – a fifteen year experience

BACKGROUND: Coronary Endarterectomy (CE) in patients undergoing coronary artery bypass graft (CABG) surgery has been shown to be beneficial in those with diffuse coronary artery disease. There are no published data on its role and benefit in patients undergoing more complex operations. We present ou...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Sanjay, Agarwala, Sandeep, Talbot, Charlie, Nair, R Unnikrishnan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291048/
https://www.ncbi.nlm.nih.gov/pubmed/18366756
http://dx.doi.org/10.1186/1749-8090-3-15
_version_ 1782152425727066112
author Kumar, Sanjay
Agarwala, Sandeep
Talbot, Charlie
Nair, R Unnikrishnan
author_facet Kumar, Sanjay
Agarwala, Sandeep
Talbot, Charlie
Nair, R Unnikrishnan
author_sort Kumar, Sanjay
collection PubMed
description BACKGROUND: Coronary Endarterectomy (CE) in patients undergoing coronary artery bypass graft (CABG) surgery has been shown to be beneficial in those with diffuse coronary artery disease. There are no published data on its role and benefit in patients undergoing more complex operations. We present our experience with CE in patients undergoing valve surgery with concomitant CABG. MATERIALS AND METHODS: Between 1989 and 2003, 237 patients underwent CABG with valve surgery under a single surgeon at our institution. Of these, 41 patients needed CE. Data was retrospectively obtained from hospital records and database. Further follow-up was obtained by telephone interview. All variables were analyzed by univariate analysis for significant factors relating to hospital mortality. Morbidity and long term survival was also studied. There were 29 males and 12 females with a mean age of 67.4 ± 8.1 and body mass index of 26.3 ± 3.3. Their mean euroscore was 7.6 ± 3.2 and the log euro score was 12.2 ± 16.1. RESULTS: Thirty-two patients were discharged from the intensive therapy unit within 48 hours after surgery. Average hospital stay was 12.7 ± 10.43 days. Thirty day mortality was 9.8%. Six late deaths occurred during the 14 year follow up. Ten year survival was 57.2% (95% CL 37.8%–86.6%). Three of the survivors had Class II symptoms, with one requiring nitrates. None required further percutaneous or surgical intervention. We compared the result with the available mortality figure from the SCTS database. CONCLUSION: Compared to the SCTS database for these patients, we have observed that CE does not increase the mortality in combined procedures. By accomplishing revascularization in areas deemed ungraftable, we have shown an added survival benefit in this group of patients.
format Text
id pubmed-2291048
institution National Center for Biotechnology Information
language English
publishDate 2008
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-22910482008-04-09 Long term survival after coronary endarterectomy in patients undergoing combined coronary and valvular surgery – a fifteen year experience Kumar, Sanjay Agarwala, Sandeep Talbot, Charlie Nair, R Unnikrishnan J Cardiothorac Surg Research Article BACKGROUND: Coronary Endarterectomy (CE) in patients undergoing coronary artery bypass graft (CABG) surgery has been shown to be beneficial in those with diffuse coronary artery disease. There are no published data on its role and benefit in patients undergoing more complex operations. We present our experience with CE in patients undergoing valve surgery with concomitant CABG. MATERIALS AND METHODS: Between 1989 and 2003, 237 patients underwent CABG with valve surgery under a single surgeon at our institution. Of these, 41 patients needed CE. Data was retrospectively obtained from hospital records and database. Further follow-up was obtained by telephone interview. All variables were analyzed by univariate analysis for significant factors relating to hospital mortality. Morbidity and long term survival was also studied. There were 29 males and 12 females with a mean age of 67.4 ± 8.1 and body mass index of 26.3 ± 3.3. Their mean euroscore was 7.6 ± 3.2 and the log euro score was 12.2 ± 16.1. RESULTS: Thirty-two patients were discharged from the intensive therapy unit within 48 hours after surgery. Average hospital stay was 12.7 ± 10.43 days. Thirty day mortality was 9.8%. Six late deaths occurred during the 14 year follow up. Ten year survival was 57.2% (95% CL 37.8%–86.6%). Three of the survivors had Class II symptoms, with one requiring nitrates. None required further percutaneous or surgical intervention. We compared the result with the available mortality figure from the SCTS database. CONCLUSION: Compared to the SCTS database for these patients, we have observed that CE does not increase the mortality in combined procedures. By accomplishing revascularization in areas deemed ungraftable, we have shown an added survival benefit in this group of patients. BioMed Central 2008-03-26 /pmc/articles/PMC2291048/ /pubmed/18366756 http://dx.doi.org/10.1186/1749-8090-3-15 Text en Copyright © 2008 Kumar et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Kumar, Sanjay
Agarwala, Sandeep
Talbot, Charlie
Nair, R Unnikrishnan
Long term survival after coronary endarterectomy in patients undergoing combined coronary and valvular surgery – a fifteen year experience
title Long term survival after coronary endarterectomy in patients undergoing combined coronary and valvular surgery – a fifteen year experience
title_full Long term survival after coronary endarterectomy in patients undergoing combined coronary and valvular surgery – a fifteen year experience
title_fullStr Long term survival after coronary endarterectomy in patients undergoing combined coronary and valvular surgery – a fifteen year experience
title_full_unstemmed Long term survival after coronary endarterectomy in patients undergoing combined coronary and valvular surgery – a fifteen year experience
title_short Long term survival after coronary endarterectomy in patients undergoing combined coronary and valvular surgery – a fifteen year experience
title_sort long term survival after coronary endarterectomy in patients undergoing combined coronary and valvular surgery – a fifteen year experience
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291048/
https://www.ncbi.nlm.nih.gov/pubmed/18366756
http://dx.doi.org/10.1186/1749-8090-3-15
work_keys_str_mv AT kumarsanjay longtermsurvivalaftercoronaryendarterectomyinpatientsundergoingcombinedcoronaryandvalvularsurgeryafifteenyearexperience
AT agarwalasandeep longtermsurvivalaftercoronaryendarterectomyinpatientsundergoingcombinedcoronaryandvalvularsurgeryafifteenyearexperience
AT talbotcharlie longtermsurvivalaftercoronaryendarterectomyinpatientsundergoingcombinedcoronaryandvalvularsurgeryafifteenyearexperience
AT nairrunnikrishnan longtermsurvivalaftercoronaryendarterectomyinpatientsundergoingcombinedcoronaryandvalvularsurgeryafifteenyearexperience