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The role of HMG-CoA reductase inhibition in endothelial dysfunction and inflammation

Statin-induced inhibition of HMG-CoA reductase reduces cholesterol production and prevents the formation of many non-steroidal isoprenoid compounds, such as farnesylpyrophosphate and geranylgeranylpyrophosphate, that act as lipid attachments for the post-translational modification of various protein...

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Detalles Bibliográficos
Autores principales:	Gelosa, Paolo, Cimino, Mauro, Pignieri, Alice, Tremoli, Elena, Guerrini, Uliano, Sironi, Luigi
Formato:	Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2007
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2291301/ https://www.ncbi.nlm.nih.gov/pubmed/18078008

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