WRN polymorphisms affect expression levels of plasminogen activator inhibitor type 1 in cultured fibroblasts

BACKGROUND: Recessive mutations in WRN gene eliminate WRN protein function (helicase) and cause Werner syndrome. One of the most important clinical features of Werner syndrome patients are the premature onset and accelerated atherosclerosis process. Studies carried out on polymorphic WRN locus have...

Descripción completa

Detalles Bibliográficos
Autores principales: Castro, Elena, Oviedo-Rodríguez, Vladimir, Angel-Chávez, Luis I
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292137/
https://www.ncbi.nlm.nih.gov/pubmed/18312663
http://dx.doi.org/10.1186/1471-2261-8-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292137/
https://www.ncbi.nlm.nih.gov/pubmed/18312663
http://dx.doi.org/10.1186/1471-2261-8-5

Ejemplares similares