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12(S)-hydroxyheptadeca-5Z, 8E, 10E–trienoic acid is a natural ligand for leukotriene B(4) receptor 2

Activated blood platelets and macrophages metabolize prostaglandin H(2) into thromboxane A(2) and 12(S)-hydroxyheptadeca-5Z, 8E, 10E–trienoic acid (12-HHT) in an equimolar ratio through the action of thromboxane synthase. Although it has been shown that 12-HHT is abundant in tissues and bodily fluid...

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Detalles Bibliográficos
Autores principales:	Okuno, Toshiaki, Iizuka, Yoshiko, Okazaki, Hiroshi, Yokomizo, Takehiko, Taguchi, Ryo, Shimizu, Takao
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292216/ https://www.ncbi.nlm.nih.gov/pubmed/18378794 http://dx.doi.org/10.1084/jem.20072329

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