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The Th17–ELR(+) CXC chemokine pathway is essential for the development of central nervous system autoimmune disease
The ELR(+) CXC chemokines CXCL1 and CXCL2 are up-regulated in the central nervous system (CNS) during multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE). However, their functional significance and the pathways regulating their expression are largely unknown...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292221/ https://www.ncbi.nlm.nih.gov/pubmed/18347102 http://dx.doi.org/10.1084/jem.20072404 |