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Polyomavirus BK with rearranged noncoding control region emerge in vivo in renal transplant patients and increase viral replication and cytopathology

Immunosuppression is required for BK viremia and polyomavirus BK–associated nephropathy (PVAN) in kidney transplants (KTs), but the role of viral determinants is unclear. We examined BKV noncoding control regions (NCCR), which coordinate viral gene expression and replication. In 286 day–matched plas...

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Detalles Bibliográficos
Autores principales:	Gosert, Rainer, Rinaldo, Christine H., Funk, Georg A., Egli, Adrian, Ramos, Emilio, Drachenberg, Cinthia B., Hirsch, Hans H.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292223/ https://www.ncbi.nlm.nih.gov/pubmed/18347101 http://dx.doi.org/10.1084/jem.20072097

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