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Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice
Rheumatoid arthritis (RA) is a common autoimmune disease that afflicts the synovium of diarthrodial joints. The pathogenic mechanisms inciting this disease are not fully characterized, but may involve the loss of tolerance to posttranslationally modified (citrullinated) antigens. We have demonstrate...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292232/ https://www.ncbi.nlm.nih.gov/pubmed/18391064 http://dx.doi.org/10.1084/jem.20072051 |