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Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice

Rheumatoid arthritis (RA) is a common autoimmune disease that afflicts the synovium of diarthrodial joints. The pathogenic mechanisms inciting this disease are not fully characterized, but may involve the loss of tolerance to posttranslationally modified (citrullinated) antigens. We have demonstrate...

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Detalles Bibliográficos
Autores principales: Hill, Jonathan A., Bell, David A., Brintnell, William, Yue, David, Wehrli, Bret, Jevnikar, Anthony M., Lee, David M., Hueber, Wolfgang, Robinson, William H., Cairns, Ewa
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292232/
https://www.ncbi.nlm.nih.gov/pubmed/18391064
http://dx.doi.org/10.1084/jem.20072051