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Lhx2 Expression Promotes Self-Renewal of a Distinct Multipotential Hematopoietic Progenitor Cell in Embryonic Stem Cell-Derived Embryoid Bodies

The molecular mechanisms regulating the expansion of the hematopoietic system including hematopoietic stem cells (HSCs) in the fetal liver during embryonic development are largely unknown. The LIM-homeobox gene Lhx2 is a candidate regulator of fetal hematopoiesis since it is expressed in the fetal l...

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Detalles Bibliográficos
Autores principales: Dahl, Lina, Richter, Karin, Hägglund, Anna-Carin, Carlsson, Leif
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292257/
https://www.ncbi.nlm.nih.gov/pubmed/18431502
http://dx.doi.org/10.1371/journal.pone.0002025