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Gene targeting in adult rhesus macaque fibroblasts

BACKGROUND: Gene targeting in nonhuman primates has the potential to produce critical animal models for translational studies related to human diseases. Successful gene targeting in fibroblasts followed by somatic cell nuclear transfer (SCNT) has been achieved in several species of large mammals but...

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Detalles Bibliográficos
Autores principales: Meehan, Daniel T, Zink, Mary Ann, Mahlen, Melissa, Nelson, Marilu, Sanger, Warren G, Mitalipov, Shoukhrat M, Wolf, Don P, Ouellette, Michel M, Norgren, Robert B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292692/
https://www.ncbi.nlm.nih.gov/pubmed/18366794
http://dx.doi.org/10.1186/1472-6750-8-31