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Experimental evolution and genome sequencing reveal variation in levels of clonal interference in large populations of bacteriophage φX174

BACKGROUND: In large asexual populations where beneficial mutations may co-occur and recombination is absent, the fate of beneficial mutations can be significantly affected by competition (i.e., clonal interference). Theoretical models predict that clonal interference (CI) can slow adaptation, alter...

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Detalles Bibliográficos
Autores principales: Pepin, Kim M, Wichman, Holly A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292699/
https://www.ncbi.nlm.nih.gov/pubmed/18366653
http://dx.doi.org/10.1186/1471-2148-8-85