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Worldwide distribution of NAT2 diversity: Implications for NAT2 evolutionary history
BACKGROUND: The N-acetyltransferase 2 (NAT2) gene plays a crucial role in the metabolism of many drugs and xenobiotics. As it represents a likely target of population-specific selection pressures, we fully sequenced the NAT2 coding region in 97 Mandenka individuals from Senegal, and compared these s...
Autores principales: | Sabbagh, Audrey, Langaney, André, Darlu, Pierre, Gérard, Nathalie, Krishnamoorthy, Rajagopal, Poloni, Estella S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292740/ https://www.ncbi.nlm.nih.gov/pubmed/18304320 http://dx.doi.org/10.1186/1471-2156-9-21 |
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