Interleukin-23 Restrains Regulatory T Cell Activity to Drive T Cell-Dependent Colitis

Interleukin-23 (IL-23) is an inflammatory cytokine that plays a key role in the pathogenesis of several autoimmune and inflammatory diseases. It orchestrates innate and T cell-mediated inflammatory pathways and can promote T helper 17 (Th17) cell responses. Utilizing a T cell transfer model, we show...

Descripción completa

Detalles Bibliográficos
Autores principales: Izcue, Ana, Hue, Sophie, Buonocore, Sofia, Arancibia-Cárcamo, Carolina V., Ahern, Philip P., Iwakura, Yoichiro, Maloy, Kevin J., Powrie, Fiona
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292821/
https://www.ncbi.nlm.nih.gov/pubmed/18400195
http://dx.doi.org/10.1016/j.immuni.2008.02.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292821/
https://www.ncbi.nlm.nih.gov/pubmed/18400195
http://dx.doi.org/10.1016/j.immuni.2008.02.019

Ejemplares similares