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Interleukin-23 Restrains Regulatory T Cell Activity to Drive T Cell-Dependent Colitis
Interleukin-23 (IL-23) is an inflammatory cytokine that plays a key role in the pathogenesis of several autoimmune and inflammatory diseases. It orchestrates innate and T cell-mediated inflammatory pathways and can promote T helper 17 (Th17) cell responses. Utilizing a T cell transfer model, we show...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292821/ https://www.ncbi.nlm.nih.gov/pubmed/18400195 http://dx.doi.org/10.1016/j.immuni.2008.02.019 |