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Assembly and Channel Opening in a Bacterial Drug Efflux Machine
Drugs and certain proteins are transported across the membranes of Gram-negative bacteria by energy-activated pumps. The outer membrane component of these pumps is a channel that opens from a sealed resting state during the transport process. We describe two crystal structures of the Escherichia col...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292822/ https://www.ncbi.nlm.nih.gov/pubmed/18406332 http://dx.doi.org/10.1016/j.molcel.2008.02.015 |