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Alendronate decreases orthotopic PC-3 prostate tumor growth and metastasis to prostate-draining lymph nodes in nude mice

BACKGROUND: Metastatic prostate cancer is associated with a high morbidity and mortality but the spreading mechanisms are still poorly understood. The aminobisphosphonate alendronate, used to reduce bone loss, has also been shown to inhibit the invasion and migration of prostate cancer cells in vitr...

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Detalles Bibliográficos
Autores principales: Tuomela, Johanna M, Valta, Maija P, Väänänen, Kalervo, Härkönen, Pirkko L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2294135/
https://www.ncbi.nlm.nih.gov/pubmed/18371232
http://dx.doi.org/10.1186/1471-2407-8-81

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