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Alendronate decreases orthotopic PC-3 prostate tumor growth and metastasis to prostate-draining lymph nodes in nude mice
BACKGROUND: Metastatic prostate cancer is associated with a high morbidity and mortality but the spreading mechanisms are still poorly understood. The aminobisphosphonate alendronate, used to reduce bone loss, has also been shown to inhibit the invasion and migration of prostate cancer cells in vitr...
Autores principales: | Tuomela, Johanna M, Valta, Maija P, Väänänen, Kalervo, Härkönen, Pirkko L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2294135/ https://www.ncbi.nlm.nih.gov/pubmed/18371232 http://dx.doi.org/10.1186/1471-2407-8-81 |
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