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Essential and distinct roles of the F-box and helicase domains of Fbh1 in DNA damage repair
BACKGROUND: DNA double-strand breaks (DSBs) are induced by exogenous insults such as ionizing radiation and chemical exposure, and they can also arise as a consequence of stalled or collapsed DNA replication forks. Failure to repair DSBs can lead to genomic instability or cell death and cancer in hi...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2294136/ https://www.ncbi.nlm.nih.gov/pubmed/18312697 http://dx.doi.org/10.1186/1471-2199-9-27 |