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Inhibition of androgen-independent prostate cancer cell growth is enhanced by combination therapy targeting Hedgehog and ErbB signalling

BACKGROUND: Prostate cancer is a leading cause of male cancer specific mortality. When cure by radical prostatectomy is not possible the next line of prostate cancer treatment is androgen deprivation. However prolonged androgen deprivation often results in relapse and androgen-independent prostate c...

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Detalles Bibliográficos
Autores principales: Shaw, Greg, Prowse, David M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2311276/
https://www.ncbi.nlm.nih.gov/pubmed/18348720
http://dx.doi.org/10.1186/1475-2867-8-3