Protein kinase A-mediated CREB phosphorylation is an oxidant-induced survival pathway in alveolar type II cells

Oxidant stress plays a role in the pathogenesis of pulmonary diseases, including fibrotic lung disease and cancer. We previously found that hydrogen peroxide (H(2)O(2)) initiates an increase in Ca(2+)/cAMP-response element binding protein (CREB) phosphorylation in C10 alveolar type II cells that req...

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Detalles Bibliográficos
Autores principales: Barlow, Christy A., Kitiphongspattana, Kajorn, Siddiqui, Nazli, Roe, Michael W., Mossman, Brooke T., Lounsbury, Karen M.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2008
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2311383/
https://www.ncbi.nlm.nih.gov/pubmed/18392938
http://dx.doi.org/10.1007/s10495-008-0203-z

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