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Flightless-I regulates proinflammatory caspases by selectively modulating intracellular localization and caspase activity
Caspase-1 and caspase-11 are proinflammatory caspases that regulate cytokine production and leukocyte migration during pathogen infection. In an attempt to identify new intracellular regulators of caspase-11, we found that Flightless-I, a member of the gelsolin superfamily of actin-remodeling protei...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2315678/ https://www.ncbi.nlm.nih.gov/pubmed/18411310 http://dx.doi.org/10.1083/jcb.200711082 |