Leptin affects endocardial cushion formation by modulating EMT and migration via Akt signaling cascades

Blood circulation is dependent on heart valves to direct blood flow through the heart and great vessels. Valve development relies on epithelial to mesenchymal transition (EMT), a central feature of embryonic development and metastatic cancer. Abnormal EMT and remodeling contribute to the etiology of...

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Detalles Bibliográficos
Autores principales: Nath, Anjali K., Brown, Rachel M., Michaud, Michael, Sierra-Honigmann, M. Rocio, Snyder, Michael, Madri, Joseph A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2315681/
https://www.ncbi.nlm.nih.gov/pubmed/18411306
http://dx.doi.org/10.1083/jcb.200708197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2315681/
https://www.ncbi.nlm.nih.gov/pubmed/18411306
http://dx.doi.org/10.1083/jcb.200708197

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