Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD

BACKGROUND: The lectin-like oxidized LDL receptor LOX-1 (encoded by OLR1) is believed to play a key role in atherogenesis and some reports suggest an association of OLR1 polymorphisms with myocardial infarction (MI). We tested whether single nucleotide polymorphisms (SNPs) in OLR1 are associated wit...

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Detalles Bibliográficos
Autores principales: Knowles, Joshua W, Assimes, Themistocles L, Boerwinkle, Eric, Fortmann, Stephen P, Go, Alan, Grove, Megan L, Hlatky, Mark, Iribarren, Carlos, Li, Jun, Myers, Richard, Risch, Neil, Sidney, Stephen, Southwick, Audrey, Volcik, Kelly A, Quertermous, Thomas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2322963/
https://www.ncbi.nlm.nih.gov/pubmed/18384690
http://dx.doi.org/10.1186/1471-2350-9-23

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