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Primate Lentiviral Vpx Commandeers DDB1 to Counteract a Macrophage Restriction

Primate lentiviruses encode four “accessory proteins” including Vif, Vpu, Nef, and Vpr/Vpx. Vif and Vpu counteract the antiviral effects of cellular restrictions to early and late steps in the viral replication cycle. We present evidence that the Vpx proteins of HIV-2/SIV(SM) promote virus infection...

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Detalles Bibliográficos
Autores principales:	Sharova, Natalia, Wu, Yuanfei, Zhu, Xiaonan, Stranska, Ruzena, Kaushik, Rajnish, Sharkey, Mark, Stevenson, Mario
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323106/ https://www.ncbi.nlm.nih.gov/pubmed/18451984 http://dx.doi.org/10.1371/journal.ppat.1000057

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