Vaccination and Timing Influence SIV Immune Escape Viral Dynamics In Vivo

CD8+ cytotoxic T lymphocytes (CTL) can be effective at controlling HIV-1 in humans and SIV in macaques, but their utility is partly offset by mutational escape. The kinetics of CTL escape and reversion of escape mutant viruses upon transmission to MHC-mismatched hosts can help us understand CTL-medi...

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Detalles Bibliográficos
Autores principales: Loh, Liyen, Petravic, Janka, Batten, C. Jane, Davenport, Miles P, Kent, Stephen J
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323283/
https://www.ncbi.nlm.nih.gov/pubmed/18225952
http://dx.doi.org/10.1371/journal.ppat.0040012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323283/
https://www.ncbi.nlm.nih.gov/pubmed/18225952
http://dx.doi.org/10.1371/journal.ppat.0040012

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