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Inhibitors of Pathogen Intercellular Signals as Selective Anti-Infective Compounds
Long-term antibiotic use generates pan-resistant super pathogens. Anti-infective compounds that selectively disrupt virulence pathways without affecting cell viability may be used to efficiently combat infections caused by these pathogens. A candidate target pathway is quorum sensing (QS), which man...
Autores principales: | Lesic, Biliana, Lépine, François, Déziel, Eric, Zhang, Jiangwen, Zhang, Qunhao, Padfield, Katie, Castonguay, Marie-Hélène, Milot, Sylvain, Stachel, Scott, Tzika, A. Aria, Tompkins, Ronald G, Rahme, Laurence G |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323289/ https://www.ncbi.nlm.nih.gov/pubmed/17941706 http://dx.doi.org/10.1371/journal.ppat.0030126 |
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