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Identification of a GTP-bound Rho specific scFv molecular sensor by phage display selection
BACKGROUND: The Rho GTPases A, B and C proteins, members of the Rho family whose activity is regulated by GDP/GTP cycling, function in many cellular pathways controlling proliferation and have recently been implicated in tumorigenesis. Although overexpression of Rho GTPases has been correlated with...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323369/ https://www.ncbi.nlm.nih.gov/pubmed/18377644 http://dx.doi.org/10.1186/1472-6750-8-34 |