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Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein

BACKGROUND: Evidence from biochemical, epidemiological and genetic findings indicates that cholesterol levels are linked to amyloid-β (Aβ) production and Alzheimer's disease (AD). Oxysterols, which are cholesterol-derived ligands of the liver X receptors (LXRs) and oxysterol binding proteins, s...

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Detalles Bibliográficos
Autores principales:	Zerbinatti, Celina V, Cordy, Joanna M, Chen, Ci-Di, Guillily, Maria, Suon, Sokreine, Ray, William J, Seabrook, Guy R, Abraham, Carmela R, Wolozin, Benjamin
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323375/ https://www.ncbi.nlm.nih.gov/pubmed/18348724 http://dx.doi.org/10.1186/1750-1326-3-5

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