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H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments
BACKGROUND: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to the examination of individual positions, the investigation of co-variation of amino acid frequencies offers insights into...
Autores principales: | Merkl, Rainer, Zwick, Matthias |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323388/ https://www.ncbi.nlm.nih.gov/pubmed/18366663 http://dx.doi.org/10.1186/1471-2105-9-151 |
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