An anatomy ontology to represent biological knowledge in Dictyostelium discoideum

BACKGROUND: Dictyostelium discoideum is a model system for studying many important physiological processes including chemotaxis, phagocytosis, and signal transduction. The recent sequencing of the genome has revealed the presence of over 12,500 protein-coding genes. The model organism database dicty...

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Detalles Bibliográficos
Autores principales: Gaudet, Pascale, Williams, Jeffery G, Fey, Petra, Chisholm, Rex L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323390/
https://www.ncbi.nlm.nih.gov/pubmed/18366659
http://dx.doi.org/10.1186/1471-2164-9-130
Descripción
Sumario:BACKGROUND: Dictyostelium discoideum is a model system for studying many important physiological processes including chemotaxis, phagocytosis, and signal transduction. The recent sequencing of the genome has revealed the presence of over 12,500 protein-coding genes. The model organism database dictyBase hosts the genome sequence as well as a large amount of manually curated information. RESULTS: We present here an anatomy ontology for Dictyostelium based upon the life cycle of the organism. CONCLUSION: Anatomy ontologies are necessary to annotate species-specific events such as phenotypes, and the Dictyostelium anatomy ontology provides an essential tool for curation of the Dictyostelium genome.

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