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The First Bioluminescence Tomography System for Simultaneous Acquisition of Multiview and Multispectral Data

We describe the system design of the first bioluminescence tomography (BLT) system for parallel acquisition of multiple bioluminescent views around a mouse in a number of spectral channels simultaneously. The primary component of this BLT system is a novel mirror module and a unique mouse holder. Th...

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Detalles Bibliográficos
Autores principales: Wang, Ge, Shen, Haiou, Durairaj, Kumar, Qian, Xin, Cong, Wenxiang
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2324039/
https://www.ncbi.nlm.nih.gov/pubmed/23165042
http://dx.doi.org/10.1155/IJBI/2006/58601
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author Wang, Ge
Shen, Haiou
Durairaj, Kumar
Qian, Xin
Cong, Wenxiang
author_facet Wang, Ge
Shen, Haiou
Durairaj, Kumar
Qian, Xin
Cong, Wenxiang
author_sort Wang, Ge
collection PubMed
description We describe the system design of the first bioluminescence tomography (BLT) system for parallel acquisition of multiple bioluminescent views around a mouse in a number of spectral channels simultaneously. The primary component of this BLT system is a novel mirror module and a unique mouse holder. The mirror module consists of a mounting plate and four mirrors with stages. These mirror stages are right triangular blocks symmetrically arranged and attached to the mounting plate such that the hypotenuse surfaces of the triangular blocks all make 45(∘) to the plate surface. The cylindrical/polygonal mouse holder has semitransparent rainbow bands on its side surface for the acquisition of spectrally resolved data. Numerical studies and experiments are performed to demonstrate the feasibility of this system. It is shown that bioluminescent signals collected using our system can produce a similar BLT reconstruction quality while reducing the data acquisition time, as compared to the sequential data acquisition mode.
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spelling pubmed-23240392008-04-22 The First Bioluminescence Tomography System for Simultaneous Acquisition of Multiview and Multispectral Data Wang, Ge Shen, Haiou Durairaj, Kumar Qian, Xin Cong, Wenxiang Int J Biomed Imaging Article We describe the system design of the first bioluminescence tomography (BLT) system for parallel acquisition of multiple bioluminescent views around a mouse in a number of spectral channels simultaneously. The primary component of this BLT system is a novel mirror module and a unique mouse holder. The mirror module consists of a mounting plate and four mirrors with stages. These mirror stages are right triangular blocks symmetrically arranged and attached to the mounting plate such that the hypotenuse surfaces of the triangular blocks all make 45(∘) to the plate surface. The cylindrical/polygonal mouse holder has semitransparent rainbow bands on its side surface for the acquisition of spectrally resolved data. Numerical studies and experiments are performed to demonstrate the feasibility of this system. It is shown that bioluminescent signals collected using our system can produce a similar BLT reconstruction quality while reducing the data acquisition time, as compared to the sequential data acquisition mode. Hindawi Publishing Corporation 2006 2006-12-04 /pmc/articles/PMC2324039/ /pubmed/23165042 http://dx.doi.org/10.1155/IJBI/2006/58601 Text en Copyright © 2006 G. Wang et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Wang, Ge
Shen, Haiou
Durairaj, Kumar
Qian, Xin
Cong, Wenxiang
The First Bioluminescence Tomography System for Simultaneous Acquisition of Multiview and Multispectral Data
title The First Bioluminescence Tomography System for Simultaneous Acquisition of Multiview and Multispectral Data
title_full The First Bioluminescence Tomography System for Simultaneous Acquisition of Multiview and Multispectral Data
title_fullStr The First Bioluminescence Tomography System for Simultaneous Acquisition of Multiview and Multispectral Data
title_full_unstemmed The First Bioluminescence Tomography System for Simultaneous Acquisition of Multiview and Multispectral Data
title_short The First Bioluminescence Tomography System for Simultaneous Acquisition of Multiview and Multispectral Data
title_sort first bioluminescence tomography system for simultaneous acquisition of multiview and multispectral data
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2324039/
https://www.ncbi.nlm.nih.gov/pubmed/23165042
http://dx.doi.org/10.1155/IJBI/2006/58601
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